If you think wearing a bicycle helmet is for wimps, think again. Joey Harrington, a 33 year old former National Football League quarterback, was struck from behind by a driver of an SUV while riding a bike. On Sunday, July 31st, 2011, Harrington was hospitalized with non-life threatening injuries including a broken collarbone, a punctured lung, and a cut on his head. The crash caused Harrington to land on the vehicle. He was upside down when he skidded off and landed on his head and shoulder. Harrington was wearing a bicycle helmet which prevented much more serious injury. Harrington is expected to be released from the hospital on Tuesday, August 02, 2011. “>
Beaten Baseball Fan Suffered Traumatic Brain Injury
Bryan Stow, 42, a San Francisco paramedic, who was attacked by two suspects on March 31st at Dodger Stadium in Los Angeles, last week has been upgraded from ‘critical’ to ‘serious’ condition but his doctors say they remain “extremely cautious about interpreting his progress”. Stow is able to open his eyes and respond to basic commands. Doctors said Stow suffered a 30-second seizure recently and underwent surgery to relieve fluid built up in this head. http://www.thirdage.com/news/bryan-stow-injured-giants-fan-undergoes-more-surgery_07-22-2011
New details of the attack, that has spurred nation-wide public outrage, were released at a bond reduction hearing on August 1st. Stow was punched on the side of his head from behind. As fellow paramedics witnessed, Stow become unconscious before he fell to the asphalt covered parking lot. Stow was unable to impede his fall. Witnesses further heard his head hit the asphalt and observed his head bounce upon hitting the ground. Once on the ground, one of the two beating suspects kicked Stow numerous times in the head. The other suspect also kicked Stow in the head. http://www.washingtonpost.com/national/court-documents-describe-attack-on-giants-fan-at-dodger-stadium/2011/08/01/gIQAuwWlnI_story.html
Battlefield Soldiers and Football Players with TBI have Higher Risk to get Dementia, Studies Show
Study: Extending time of stroke drug treatment OK
By ALICIA CHANG
AP Science Writer
LOS ANGELES (AP) _ Stroke sufferers can still benefit from clot-busting medicine even if they receive it an hour or so beyond the current three-hour window after symptoms start, an important new study suggests.
The finding could potentially extend treatment to thousands more people each year and prevent many from being left disabled. However, it does not change long-standing advice that stroke victims seek immediate help if they feel sudden numbness or weakness in the face, arm or leg.
“Don’t wait,” said Dr. Larry Goldstein, director of Duke University’s stroke center and a spokesman for the American Stroke Association. “If you think you are having symptoms, call 911.”
The study by European doctors found that the clot dissolver could safely be given up to 4½ hours after the start of symptoms. Results were published in Thursday’s New England Journal of Medicine.
Stroke is the nation’s No. 3 killer and the leading cause of disability such as paralysis or speech loss. More than 700,000 Americans suffer a new or recurrent stroke each year and more than 150,000 die. The most common strokes result from a blood clot blocking an artery supplying blood to the brain, starving brain cells of oxygen.
The best treatment is giving patients the drug TPA to break up the clot and open the artery. A large federal study in 1995 showed that people fared better when given the drug within three hours of the start of a stroke. Beyond that, studies have shown the drug can raise the risk of dangerous bleeding in the brain and may not be as effective.
However, only about a third of stroke victims seek help that fast, and fewer than 5 percent get TPA now. Some doctors have been trying to push the time limit, and the new study is the largest and most rigorous to test that approach.
Doctors randomly assigned 821 stroke patients in Europe who were not treated within three hours to receive an intravenous dose of TPA or a dummy drug up to 4½ hours after symptoms started.
Doctors found those given TPA fared better — 52 percent survived without major disability compared with 45 percent of the others. The drug group had more cases of bleeding in the brain — 27 percent versus 18 percent. However, it was serious in only about 2 percent. The death rate was similar in both groups.
The study was funded by Boehringer Ingelheim Pharmaceuticals Inc., which markets TPA as Actilyse overseas. TPA is sold in North America by Genentech Inc. as Activase.
Last week, the same researchers reported similar results in a less rigorous observational study of 664 stroke patients also given TPA after three hours.
Dr. Lee Schwamm, director of Massachusetts General Hospital’s acute stroke program, estimated that nearly 20,000 more patients a year could be treated under the time extension.
“I strongly believe it has the potential to have a major impact on practice” in the United States, said Schwamm, who had no role in the research.
Some experts worry that some patients and doctors may take their time treating strokes given the extra window.
“It is very clear that our focus must remain on the door-to-needle time. Every minute matters during a stroke,” Dr. Patrick Lyden, head of the University of California, San Diego stroke center, wrote in an accompanying editorial.
Stroke neurologist Dr. Walter Koroshetz of the National Institutes of Health said treatment guidelines deserve a fresh look “to try to break this three-hour barrier.”
Koroshetz said it’s not clear which patients might benefit most from the extra time. Since the European study focused on mild stroke cases, it’s unknown if severe stroke victims would also benefit, he said.
Dr. Kenneth Gaines, stroke director at New Orlean’s Ochsner Medical Center, said he might be more willing to consider giving TPA in borderline cases. But he remained concerned about the bleeding side effects.
“The real solution is to move faster,” Gaines said. “There is diminishing return the longer you delay treatment.”
___
On the Net:
NEJM: http://content.nejm.org
American Stroke Association: http://www.strokeassociation.org
(This version corrects that 1995 study found that people fared better with quick drug treatment, not that it saved lives.)
Copyright 2008 The Associated Press.
Brain Injury and Malingering – A Dangerous Deceit
The more clever defense doctor will not go so far as to outright claim that a plaintiff has malingered, but suggest it, and then to base such suggestion on what the doctor deems to be inconsistent effort throughout the battery of tests. I discussed in my previous blog the problem that fatigue creates in interpreting neuropsychological results, especially claims that someone did not give best effort. If you progressively tire, you invariably will do worse on tests given later in a battery than earlier.
But a progressive decline in test performance is not the only pattern that can be expected in a brain injured person. In my way of looking at it, a significantly brain injured person can be expected to be inconsistent, because virtually every symptom of brain injury can affect how a person feels, thinks and reacts at any given moment. And that symptom can ebb and flow, both within a given test, across a test battery or from one day of testing to another.
Another common problem with malingering tests is that they are based upon the theory that such test is so easy that even a severely brain injured person would pass it. Well that has some superficial merit, but when they are talking about severely brain injured individuals, they are talking about someone who in most cases, had a focal injury that resulted in an increase in intracranial pressure, resulting in a coma. Such people often have a different set of problems, more severe in the focal area of their injury, but with not as severe of problems in other areas. One cannot assume, despite the logic of it, that a person with a severe brain injury will have a worse outcome than someone with a significant concussion. I have written for years about the Miracles and Tragedies of Brain Injury.
The third problem with malingering claims, is that they only look at the few tests in the battery that are considered malingering or effort tests, and ignore the dozens of other tests in the battery that require considerably more effort than the “effort” test. If properly designed, an effort test should look just like all of the others. So if a person was truly malingering, wouldn’t they do poorly on all the tests, not just the “effort” tests. Yet in every single case I have every heard a defense neuropsychologist raise the malingering specter, there were subtests by my client, and usually many, many subtests, where my client did extremely well. If they were malingering, why did they do well on these tests?
Bottom line, all malingering tests are fatally flawed because there is no actual research on people who actually malingered. The research that is done is done on experimental subjects who are told to pretend to be malingered. In my favorite malingering study, the instruction to exaggerate your claims, but in a way not to get caught, was given to an equal number of brain injured persons and non-brain injured persons. In this study, it was only the brain injured persons got caught. In all other studies, the pretend malingerers were instructed to “act” like a malingerer. But a true malingerer would not want to get caught. The realities are that the only time a malingering test is ever likely to catch someone for true exaggeration, it is likely to catch a brain injured person, because they lack the judgment to do it in a way they won’t get caught.
Brain Injury Awareness Month Wisconsin Lectures
I will greatly appreciate your assistance in promoting advertisement of the Brain Awareness Weeks activities, that will take place next week at the Milwaukee Veterans Administration.
We are organizing a few lectures on Traumatic Brain Injury (TBI). These lectures are scheduled in the context of outreach activities of the Milwaukee Chapter of the Society for Neuroscience, to patients and families, as well as the general public and health care providers. Next week is the Brain Awareness Week (http://www.sfn.org/baw/), which provides a great opportunity for educational and outreach activities.
We need to increase the awareness of people on brain diseases and injuries, and inform clinicians, and patients and families about what modern research on brain/nervous system and clinical neuroscience can do for them, and to increase their awareness on resources and support systems.
We have a lot of veterans who have survived Traumatic Brain Injuries, and their suffering has great impact in their own life, and their families’ lifes (not to mention the burden to our health care system, in general).
So, we think that patients, families and health care providers will benefit a lot from hearing a few experts present their experiences, insights, and some pertinent information and helpful material. The Brain Injury Association of Wisconsin is willing to contribute also.
So, we need to advertise the lecture to include an audience as large as possible: This will be of interest to several practitioners involved in the care of veterans with TBI, as well.
These lectures are to be held at the Matousek auditorium.
Monday, March 10, 12-1 pm: “What physical therapy has to offer to patients with Traumatic Brain Injury”. By Jennifer Batie, PT, CJ Zablocki VAMC Dept of Physical Therapy
Tuesday, March 1, 11-12: “Current advances in pain management”. By H.
Shankar, MD, Pain Medicine Specialist, Assistant professor, CJ Zablocki VA Pain Clinic
Thursday, March 13, 12:30-1:30: “Battle mind: Traumatic Brain Injury and post-combat stress”. By Kenneth Lee, MD, National Surgeon, Spinal Cord Injury Unit, CJ Zablocki VAMC
Friday, March 14, 12-1 pm: “Resources and support for people with Traumatic Brain Injury and families”. Will be presented by speakers from the Milwaukee Chapter of the Society for Neuroscience (C. Sarantopoulos, MD, PhD), from the Brain Injury Association of Wisconsin (Pat David, BIA Director – confirmation pending) and the CJ Zablocki VAMC.
Your help will be highly appreciated,
Thanks,
Constantine Sarantopoulos, MD, PhD
President, Milwaukee Chapter of the Society for Neuroscience Director, CJ Zablocki VAMC Pain Clinic Associate Professor of Anesthesiology, and Pharmacology & Toxicology Department of Anesthesiology Medical College of Wisconsin
Dear Dr. Sarantopoulos, MD, PhD:
Thank you for this notification. I will make my best efforts to attend Thursday’s lecture Dr. Lee on TBI and combat stress, as the overlap between organic brain injury and emotional issues is one of my greatest areas of interest.
Brain Injury Awareness Month
To celebrate March as Brain Injury Awareness Month, the Congressional Brain Injury Task Force is hosting a “2008 Brain Injury Awareness Day,” on Wednesday, March 12, 2008, on Capitol Hill.
Multiple events are planned, which are designed to educate Members of Congress and their staff about brain injury. These events include an Awareness Day Fair, which will feature exhibits and informational materials from individuals and organizations working in the field of brain injury. The day will also include a Congressional Briefing focused on the topic of “Traumatic Brain Injury and Community Needs.” The end of the day will feature an early-evening Congressional Reception sponsored by various national advocacy organizations, including the National Brain Injury Treatment and Training Foundation (NBIRTT), the Brain Injury Association of America (BIAA), the National Disability Rights Network (NDRN) and the National Association of State Head Injury Administrators (NASHIA).
BIAA invites all advocates to attend “2008 Brain Injury Awareness Day” events, and help educate Members of Congress and their staff. The Day also represents an important opportunity to network with others interested in helping increase brain injury awareness.
2008 Brain Injury Awareness Day Schedule of Events
Brain Injury Awareness Fair
10:00 a.m. – 2:00 p.m.
First Floor Foyer of the Rayburn House Office Building
Congressional Briefing on “Traumatic Brain Injury and Community Needs”
3:00 p.m. – 4:00 p.m.
1116 Longworth House Office Building
Congressional Reception Celebrating Brain Injury Awareness Day
5:00 p.m. – 6:30 p.m.
2105 Rayburn House Office Building
Please RSVP by Monday, March 3, 2008, to Hope Mandel in Congressman Bill Pascrell’s office if you wish to attend and/or exhibit materials during the Awareness Fair. You may also contact Hope at (202) 225-5751 or Becky Wolfkiel in Congressman Platts’ office at (202) 225-5836 with questions or for more information. In addition, as always, you may contact Laura Schiebelhut, BIAA’s Director of Government Affairs, at lschiebelhut@biausa.org, or 703-761-0750 ext. 637, for further clarification.
Gronwall on Amnesia
The book I picked was Wrightson and Gronwall, Mild Head Injury, Oxford, 1999. Click here to order this book.
This book is one of the great literature contributions to brain damage research. Dorothy Gronwall, a neuropsychologist from New Zealand, in conjunction with her colleague Philip Wrightson, a neurologist, have truly described and captured the essence of subtle brain injury in this inexpensive, 180 page text. No one who practices in the field of brain injury should be allowed to work with any survivor of such injury, without being able to grasp every concept in this book. It would be so simple to simply add a one hour exam on the contents of this book, to the board certification in neurology, psychiatry, emergency medicine and neuropsychology. The quality of diagnosis of brain damage would go up exponentially if such requirement were added. If you have a neurolawyer, demand that he/she gets and understands this book.
I opened to page 23, and here is what I had previously highlighted from such page:
“Clinical studies of amnesia in the period immediately after injury have shown that it takes some minutes for both pre- and post-traumatic amnesia to be established. In a study in which footballers (soccer players) were tested immediately after a mild head injury there was at first good recall of what had happened before the accident; retrograde amnesia (after the event) then developed after a few minutes (Yarnell and Lynch 1970). Another study examined ‘islands’ of recollection during a period of post-traumatic amnesia. These were almost all in the first quarter of the period, suggesting that it took some time for recall to be blocked.
“Plainly the injury has set in motion processes that are much slower than the one responsible for the initial loss of consciousness…. It may be that a chain of chemical changes has been initiated that needs time for development before it can inhibit neuronal function.”
I discuss on my Concussion Clinic videos at length (sorry if it is too much length) the role of adrenaline in assisting memory of the time frame right around the event itself. As we move forward in our research of concussion, and make attempts to better determine the potential for long term deficits – or perhaps just adjustment disorders related to the interplay of organic brain damage and emotional issues – we must focus on proper tests of amnesia by those who do the first intake post injury. Why is it so hard to incorporate into the emergency room protocol detailed questions about what the person remembers from 15 minutes post accident until the point in time they are being evaluated in the ER?
All of the neuropsychological tests ever invented, could not match the diagnostic value of 10 more questions about post-injury memory, well documented and recorded on the day of the event.
Iraq Brain Injury Research Provides More Evidence Re the Process of Brain Injury
In research summarized at http://www.jhu.edu/~jhumag/0208web/wholly.html#apl researchers at Johns Hopkins are saying that “Blast exposure, especially repeated exposure, can cause brain damage so subtle that soldiers may not realize they’ve been wounded. Ibolja Cernak, director of the Biomedicine Business Area at the Applied Physics Laboratory, says that these mild brain injuries can lead to gradual neurodegeneration, similar to Alzheimer’s disease.
The main researcher on this work is Ibolja Cernak, director of the Biomedicine Business Area at the Applied Physics Laboratory, at Johns Hopkins.
While there has been little controversy that blasts can cause brain damage, even without a direct blow to the head, presumably from the rapid jostling of the brain matter, inside of the skull. The Johns Hopkins story explains:
“The prevailing argument has been that waves of compressed air emanating from the blast shake the skull with enough force to strain or stretch the brain, not unlike what happens in a bad car crash. ‘It’s like a turbo-charged whiplash,” says Ross Bullock, a professor in the Department of Neurological Surgery at the University of Miami.”
But Cernak’s research posits that the blast energy is transferred in waves to the large blood vessels, which bring blood to the brain. She claims that the drastic pressure changes and rushes of blood thru these vessels from the blast, then damage the small vessels within the brain and the adjacent tissue. While not clearly more complex, analogize this to getting a bloody nose, following a series of violent sneezes.
There clearly is historical evidence to support this as an additive theory as to how the brain gets injured in combat. One of the frustrating things about modern brain injury research, is that it is done with so little historical perspective on what was known about brain damage from what I would call the “collective common sense” of centuries of working with people who were “quite right in the head” after combat. The whole concept of shell shock evolved not just because soldiers were injured by the enemies shells, but also were exposed to brain damage, from being on the sending end of shelling. Sailors on British ships of the line, were known to be at risk of getting funny, if allowed to work below deck for too long.
Neuro Docs, the Difficulty in Keeping them Straight
It sometimes feels to me, and I am sure as often to the readers of my various web pages, that there are just too many specialities with the word neuro in them. I sometimes have a hard time sorting out the neuro this’s from the neuro thats. Sometimes the specialities can’t even agree on how to spell their speciality. Take for example, the neurootologists, who are specialists in the vestibular system. The same peer reviewed literature will spell the word: neuro-otologist, neurootologist (my preferred spelling) and neurotologists.
Any way, here is my “frontal lobe test” for myself: Name all of the neuro docs I can type in 30 seconds:
neurologist
neuropsychologist
neurootologist
neuroradiologist
If you gave me extra time, I would add… neurosurgeon, neuropsychiatrist, neurobehavioral scientist, and neurolawyer. But I am not sure that the last two are in the actual book (if there were one.)
Neurologist. Most people understand what a neurologist is – a medical doctor who specializes in the neurological system. Most people interested in brain injury don’t understand that the study of neurology is so broad that brain injury only makes up about 1% of what these doctors do. To improve your odds, try to find a “behavioral neurologist.”
Neuropsychologists – these are not medical doctors, but psychologists, who at their best are neurobehaviorists, and at their worst, are test administers, who will take the concept of lieing with statistics to obscene proportions. Neuropsychology is fundamentally based upon the theory that brain pathologies, even though they cannot be directly seen in live subjects, leave behind patterns of behavior that can pinpoint where the pathology is. In its most basic form, it is based on written tests, which will show a pattern of results, where the areas of the brain affected by the pathology, will cause the test subject to do abnormally worse on the test. But any neuropsychologist worth your time, will clearly realize that the role of neuropsychology is not to administer and interpret tests, but to do a full “neuropsychological assessement” that is not a statistical process, but an analysis of all of the “footprints of pathology”, that the written test patterns, are only a small proportion of. In the coming days, I will devote an entire blog (or perhaps series of blogs) to neuropsychology, the hope of my youth as a plaintiff’s lawyer, and the bain of my maturity as one. For more on my theory of the “footprints of pathology”, click here.
Neurootologists are doctors who specialize in the vestibular system, the remarkable and complex way in which your inner ear provides the body with a gyroscope. For more on the vestibular system, click here. Some of the best neurootologists are the ones that started as neurologists, and became more specialized in the disorders of balance and vertigo, but EMT doctors who did a fellowship in the vestibular system qualify as neurootologists as well.
Neuroradiologists are radiologists who specialize in the brain and spine. Radiologists are doctors who specialize in reading diagnostic tests such as XRay, CT scans and MRI. Most of the work of the modern neuroradiologist is in CT and especially high field strength MRI. For more on neuroradiology, click here.
Neurosurgeons are surgeons who do brain and spinal surgery.
Neuropsychiatrists are psychiatrists who cross over into the field of neurology and neurobehavior, where there is an interplay between emotional/psychiatric disease and organic processes within the brain. The irony of course in that definition is that it should apply to all brain specialties, as it is “all in the head”. Again, a topic for a blog of its own, more properly a book of its own.
Neurobehavioral scientist is somewhat my own term. I think it is the role that neuropsychologists should play, on an increasing level. The most important “footprint of pathology” is the change in a person’s behavior, and particularly that change in behavior in the real world. The problem with neurobehavioral science, is that it doesn’t reduce itself to statistical analysis, doesn’t make for definitive research studies and requires subjective analysis. Well, the reason these doctors went to school for all these years, is that they could use subjective judgment to make complicated diagnosis. The human mind is far too complex to diagnose the interplay between organic pathology and emotions, without subjective judgments of trained and experienced professionals. If you doctor is not a neurobehavioral scientist, you have the wrong doctor.
Neurolawyer? There is no such specialization, at least not a recognized one. I consider myself to be a neurobehavioral expert, but not a medical expert, nor a psychological one. I work almost exclusively in the field of brain damage, and have learned from and challenged the best medical/psychological minds in the country with my inquiries, questions and depositions. But most of what I have learned has been from you – the survivors of brain injury and the family members of those survivors. I keep learning, I keep writing, I keep asking the tough questions, the questions that because I cannot be pigeon holed into any of the above specialities, often are questions that require thought, and hopefully research to answer.